Macromolecular Assemblies Highlighted
نویسندگان
چکیده
منابع مشابه
Using lanthanoid complexes to phase large macromolecular assemblies
Lanthanoid ions exhibit extremely large anomalous X-ray scattering at their L(III) absorption edge. They are thus well suited for anomalous diffraction experiments. A novel class of lanthanoid complexes has been developed that combines the physical properties of lanthanoid atoms with functional chemical groups that allow non-covalent binding to proteins. Two structures of large multimeric prote...
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Mass spectrometry not only plays a crucial role in the identification of proteins involved in the intricate interaction networks of the cell, but also is increasingly involved in the characterization of the non-covalent complexes formed by interacting partners. Recent developments have enabled the use of gas phase dissociation to probe oligomeric organization and topology, and increased underst...
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atomic and ultrafast time resolution combined are lacking, yet will become available. Femtosecond electron diffraction (FED) is a promising tabletop technique with complementary features to XFELmeasurements [Miller, R.J.D, Science, 2014, 343, 1108-1116]. It combines the high spatial resolution of diffraction methods with the high temporal resolution of femtosecond optical spectroscopy. The curr...
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We have developed conical tomography for the transmission electron microscope to study a wide range of structures at molecular resolution. Unlike the other related types of tomography (single and double-axis tilt), conical tomography has a higher throughput and more importantly, produces reconstructions that are isotropic in the x-y plane with a resolution of 2-3nm [1]. Using a custom made tilt...
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ژورنال
عنوان ژورنال: Structure
سال: 2005
ISSN: 0969-2126
DOI: 10.1016/j.str.2005.02.010